Driving under the influence of any medication which impairs your driving is permitted:
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If you have a medical prescription.
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If you feel alert.
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If you have an emergency.
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Under no circumstances.
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Explanation
It is always illegal to drive under the influence of any substance - including prescription or over-the-counter medication - if it impairs your ability to drive safely. Even if a doctor prescribed the medication, you are still responsible for knowing how it affects you. If it causes drowsiness, slowed reaction times, or poor coordination, you must not drive.
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Other questions in the same category: Alcohol and Drug Effects on Driving
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This question appears in the following DMV practice tests: