This road sign means:

This road sign indicates that drivers are about to enter a one-way street the wrong way. In other words, they are about to drive in the opposite direction of traffic flow. This is extremely dangerous and illegal, as it can lead to head-on collisions with other vehicles. If you see red reflectors facing you on the lane lines, or red “Wrong Way” and “Do Not Enter” signs, turn off of the one-way street immediately or get into the proper lane of a two-way street.

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